Abstract: In the report， in order to investigate the effects of prebiotics on growth and immune antioxidant of Babyloniaareolata， 600 healthy B. areolate， whose average body weight are 3.27±0.12 g， were divided into 5 groups： one control group fed with basal diet and four experimental groups fed with basal diets added with 0.5% chitosan oligosaccharide （COS）， mannooligosaccharide （MOS）， xylo-oligosaccharide （XOS） or fructooligosaccharide （FOS）， respectively， there are 3 parallels in each group and 40 experimental snails in each parallel. After continuous feeding for 4 weeks， the growth， immunity， and antioxidant indexes of each group， were measured. The results showed that the weight gain rate and specific growth rate of B. areolata in the COS group are significantly higher than those in the control group （P<0.05）. The activities of α-amylase （AMS） and lipase （LPS） are significantly increased in all prebiotic supplemented groups. The activities of acid phosphatase （ACP） and alkaline phosphatase （AKP） in the COS group are the highest among all groups， which was also significantly higher than those in the control group （P<0.05）； the XOS and COS group were the top two groups in lysozyme （LZM） contents. Both exhibiting significantly higher LZM contents than that in the control group （P<0.05）. The superoxide dismutase （SOD） in all prebiotic supplemented groups are significantly higher than that in the control group （P<0.05）， while the content of malondialdehyde （MDA） of all prebiotic supplemented groups are significantly lower than that in the control group （P<0.05）； the peroxidase （POD） activities in COS groups are significantly higher than that in the control group （P<0.05）； the catalase （CAT） activities in COS， FOS and MOS groups are all significantly higher than that in the control group （P<0.05）， with COS group being the highest； the total antioxidant （T-AOC） capacity of COS， XOS and FOS group are all significantly higher than the control group （P<0.05）， with COS group being the highest， followed by the XOS and FOS groups. The survival rate after air exposure in the COS group was the highest， followed by the XOS group， and the survival rates after air exposure in both COS group and XOS group are significantly higher than that of the control group （P<0.05）. In conclusion， the four prebiotics all exhibited beneficial effects on improving the growth， immunity and antioxidant capacity of B. areolata. Among them， COS and XOS had the best effects on promoting growth， enhancing antioxidant capacity and resisting air exposure stress. Our fingdings will provide foundation for developing effective immune enhancers and antioxidant additives in B. areolata farming.